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TNNI3 抗体 (pSer23, pSer24)

This anti-TNNI3 antibody is a 兔 多克隆 antibody detecting TNNI3 in WB 和 ELISA. Suitable for 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN6254118
发货至: 中国

Quick Overview for TNNI3 抗体 (pSer23, pSer24) (ABIN6254118)

抗原

See all TNNI3 抗体
TNNI3 (Cardiac Troponin I (TNNI3))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This TNNI3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pSer23, pSer24

    特异性

    Specific for endogenous levels of the ~25 kDa cardiac troponin I protein phosphorylated at Ser23/24. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    human, non-human primate

    产品特性

    Our Troponin I (cardiac) Ser23/24 rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Troponin I (cardiac) Ser23/24 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

    纯化方法

    Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

    免疫原

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser23/24 of mouse troponin 1, cardiac (cTnI), conjugated to keyhole limpet hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

    有效期

    12 months
  • Lin, Schmidt, Fritz, Jeong, Cammarato, Foster, Biesiadecki, McKinsey, Woulfe: "Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity." in: Journal of molecular and cellular cardiology, Vol. 139, pp. 135-147, (2020) (PubMed).

    Woulfe, Ferrara, Pioner, Mahaffey, Coppini, Scellini, Ferrantini, Piroddi, Tesi, Poggesi, Jeong: "A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study." in: Frontiers in cardiovascular medicine, Vol. 6, pp. 12, (2019) (PubMed).

  • 抗原

    TNNI3 (Cardiac Troponin I (TNNI3))

    别名

    TNNI3

    背景

    Synonyms: cardiac muscle antibody, Cardiac troponin I antibody, Cardiac Troponin I antibody, cardiomyopathy dilated 2A (autosomal recessive) antibody, Cardiomyopathy familial hypertrophic 7 included antibody, CMD1FF antibody, CMD2A antibody, CMH7 antibody, cTnI antibody, Familial hypertrophic cardiomyopathy 7 antibody, MGC116817 antibody, RCM1 antibody, Tn1 antibody, Tni antibody, TNN I3 antibody, TNNC 1 antibody, TNNC1 antibody, TNNI3 antibody, TNNI3_HUMAN antibody, Troponin I antibody, Troponin I cardiac antibody, Troponin I cardiac muscle antibody, Troponin I cardiac muscle isoform antibody, Troponin I type 3 cardiac antibody, troponin I cardiac 3 antibody, TroponinI antibody, Troponin I type 3 (cardiac) antibody

    Description Logic: Our Troponin I (cardiac) Ser23/24 rabbit polyclonal phosphospecific primary antibody is produced . It detects Troponin I (cardiac) Ser23/24 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

    Gene Name Alternatives: TNNI3

    分子量

    25 kDa

    基因ID

    21954

    UniProt

    P48787
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