TNNI3 抗体 (pSer23, pSer24)
Quick Overview for TNNI3 抗体 (pSer23, pSer24) (ABIN6254118)
抗原
See all TNNI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer23, pSer24
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特异性
- Specific for endogenous levels of the ~25 kDa cardiac troponin I protein phosphorylated at Ser23/24. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- human, non-human primate
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产品特性
- Our Troponin I (cardiac) Ser23/24 rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Troponin I (cardiac) Ser23/24 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
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纯化方法
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser23/24 of mouse troponin 1, cardiac (cTnI), conjugated to keyhole limpet hemocyanin (KLH).
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亚型
- IgG
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应用备注
- 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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有效期
- 12 months
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: "Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity." in: Journal of molecular and cellular cardiology, Vol. 139, pp. 135-147, (2020) (PubMed).
: "A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study." in: Frontiers in cardiovascular medicine, Vol. 6, pp. 12, (2019) (PubMed).
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: "Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity." in: Journal of molecular and cellular cardiology, Vol. 139, pp. 135-147, (2020) (PubMed).
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- TNNI3 (Cardiac Troponin I (TNNI3))
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别名
- TNNI3
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背景
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Synonyms: cardiac muscle antibody, Cardiac troponin I antibody, Cardiac Troponin I antibody, cardiomyopathy dilated 2A (autosomal recessive) antibody, Cardiomyopathy familial hypertrophic 7 included antibody, CMD1FF antibody, CMD2A antibody, CMH7 antibody, cTnI antibody, Familial hypertrophic cardiomyopathy 7 antibody, MGC116817 antibody, RCM1 antibody, Tn1 antibody, Tni antibody, TNN I3 antibody, TNNC 1 antibody, TNNC1 antibody, TNNI3 antibody, TNNI3_HUMAN antibody, Troponin I antibody, Troponin I cardiac antibody, Troponin I cardiac muscle antibody, Troponin I cardiac muscle isoform antibody, Troponin I type 3 cardiac antibody, troponin I cardiac 3 antibody, TroponinI antibody, Troponin I type 3 (cardiac) antibody
Description Logic: Our Troponin I (cardiac) Ser23/24 rabbit polyclonal phosphospecific primary antibody is produced . It detects Troponin I (cardiac) Ser23/24 and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
Gene Name Alternatives: TNNI3
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分子量
- 25 kDa
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基因ID
- 21954
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UniProt
- P48787
抗原
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